Oxidant/Anti-Oxidant Status in Rats Exposed to Simulated Weightlessness by Hind-Limb Unloading and Reloading

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Oxidant/Anti-Oxidant Status in Rats Exposed to Simulated Weightlessness by Hind-Limb Unloading and Reloading

Hindlimb suspension or better known as hind-limb unloading (HLU) of rats is a validated model representing weightlessness, simulating microgravity. This is accomplished by removal of weight-bearing loads from hindquarters producing a cephalic fluid shift. The current study examines whether exposure to microgravity by hind-limb unloading will activate oxidant/antioxidant defense system. Tissue l...

متن کامل

Electrical impedance alterations in the rat hind limb with unloading.

OBJECTIVES Methods are needed for quantifying muscle deconditioning due to immobilization, aging, or spaceflight. Electrical impedance myography (EIM) is one technique that may offer easy-to-follow metrics. Here, we evaluate the time course and character of the change in single- and multi-frequency EIM parameters in the hind-limb suspension model of muscle deconditioning in rats. METHODS Sixt...

متن کامل

Bone changes during simulated weightlessness in rats.

Weightless environment due to prolonged Space mission results in decreased mineralisation of the weight bearing bones. Hind limb unweighting (HU) in rats by tail suspension was used to simulate the effect of weightlessness on tibia. Adult male albino rats were divided into two groups as (i) Control (CON, n = 12) and (ii) HU for 15 days (HU, n = 18). After 15 days of HU tibia from all the animal...

متن کامل

Altered Cellular Kinetics in Growth Plate according to Alterations in Weight Bearing

PURPOSE To examine the effects of change in weight bearing on the growth plate metabolism, a simulated animal model of weightlessness was introduced and the chondrocytes' cellular kinetics was evaluated. MATERIALS AND METHODS Unloading condition on the hind-limb of Sprague-Dawley rats was created by fixing a tail and lifting the hind-limb. Six rats aged 6 weeks old were assigned to each group...

متن کامل

Orthotopic hind-limb transplantation in rats.

Composite tissue allotransplantation (CTA) now represents a valid therapeutic option after the loss of a hand, forearm or digits and has become a novel therapeutic entity in reconstructive surgery. However, long term high-dose multi-drug immunosuppressive therapy is required to ensure graft survival, bearing the risk of serious side effects which halters broader application. Further progression...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Open Clinical Chemistry Journal

سال: 2008

ISSN: 1874-2416

DOI: 10.2174/1874241600801010047